HCA Data Explorer

A Cellular Atlas of Pitx2-Dependent Cardiac Development.

Updated July 19, 2023

Single-cell RNA sequencing was applied to study the role of Pitx2 expression in heart development in mice. Over 75,000 single cardiac cell transcriptomes between two key developmental timepoints in control and Pitx2-null embryos were amplified and sequenced.

James F MartinBaylor College of Medicinejfmartin@bcm.edu
Matthew C Hill1
Zachary A Kadow1
Lele Li1
Tien T Tran1
Joshua D Wythe1
James F Martin (Principal Investigator)1
1Baylor College of Medicine
Ami E Day

To reference this project, please use the following link:

https://explore.data.humancellatlas.dev.clevercanary.com/projects/7027adc6-c9c9-46f3-84ee-9badc3a4f53b
None
INSDC Project Accessions:
SRP198380
GEO Series Accessions:
GSE131181
INSDC Study Accessions:
PRJNA542873

Downloaded and exported data is governed by the HCA Data Release Policy and licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). For more information please see our Data Use Agreement.

Atlas

None

Analysis Portals

None

Project Label

Pitx2DevelopingHeart

Species

Mus musculus

Sample Type

specimens

Anatomical Entity

heart

Organ Part

Unspecified

Selected Cell Types

Unspecified

Disease Status (Specimen)

normal

Disease Status (Donor)

normal

Development Stage

2 development stages

Library Construction Method

10X 3' v2 sequencing

Nucleic Acid Source

single cell

Paired End

false

Analysis Protocol

optimus_post_processing_v1.0.0, optimus_v4.2.2

File Format

5 file formats

Cell Count Estimate

75.0k

Donor Count

17
bam12 file(s)csv.gz6 file(s)fastq.gz24 file(s)loom13 file(s)xlsx1 file(s)