HCA Data Explorer

Fate-mapping within human iPSC-derived kidney organoids reveals conserved mammalian nephron progenitor lineage relationships.

Updated December 1, 2022

Reprogramming, CRISPR/Cas9 gene-editing, organoid technologies and single-cell RNA sequencing technology were combined to study the nephron lineage in a human context.

Sara E HowdenMurdoch Children's Research Institutesara.howden@mcri.edu.au
Melissa H LittleMurdoch Children's Research Institutemelissa.little@mcri.edu.au
Sara E Howden1
Jessica M Vanslambrouck1
Sean B Wilson1
Ker Sin Tan1
Melissa H Little1
1Murdoch Children's Research Institute
Ami Day

To reference this project, please use the following link:

https://explore.data.humancellatlas.dev.clevercanary.com/projects/b7259878-436c-4274-bfff-ca76f4cb7892
None
INSDC Project Accessions:GEO Series Accessions:INSDC Study Accessions:

Atlas

None

Analysis Portals

None

Project Label

GSE119561_KidneyOrganoidsNephronLineage

Species

Homo sapiens

Sample Type

organoids

Anatomical Entity

skin of body

Organ Part

skin of prepuce of penis

Selected Cell Types

Unspecified

Model Organ

kidney

Disease Status (Specimen)

normal

Disease Status (Donor)

normal

Development Stage

human adult stage

Library Construction Method

10x 3' v2

Nucleic Acid Source

single cell

Paired End

false

Analysis Protocol

analysis_protocol

File Format

4 file formats

Cell Count Estimate

5.4k

Donor Count

1
fastq.gz10 file(s)mtx.gz2 file(s)tsv.gz4 file(s)xlsx1 file(s)